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Creatine Kinase

3008

cpt

normal turn-around time

assays included

specimen type

minimum required

CK

82550

24 hours

CK

Serum or Plasma

1 mL of serum or heparinized plasma

collection instructions

  • Collect blood in a serum separator tube (SST) or a lithium heparin tube.

  • Allow the blood to clot at room temperature for 30 minutes if using an SST.

  • Centrifuge and separate serum or plasma from cells within 2 hours of collection.

  • Transport the specimen at 2-8°C if not tested within 2 hours.

collection instructions

  • Hemolysis: Red blood cell destruction can affect test results.

  • Clotted Specimen: Plasma specimens must be anticoagulated.

  • Improper Labeling: Specimen must be labeled with at least two patient identifiers.

  • Insufficient Quantity: Volume less than 1 mL may not be sufficient for all tests.

  • Delayed Transportation: Specimens must be processed and tested within the specified time frame to ensure accuracy.

  • Serum or plasma must be separated from cells within 2 hours and kept refrigerated if there is any delay in testing.

  • Lipemia: Excessive fat in the blood can interfere with certain test results

clinical significance

The Creatine Kinase (CK) test measures the levels of CK, an enzyme found mainly in the heart, brain, and skeletal muscles. Elevated levels of CK can indicate muscle damage or injury,
such as in myocardial infarction (heart attack), muscular dystrophy, inflammatory muscle diseases (myositis), and
strenuous exercise. It is also used to monitor muscle damage during certain medical treatments.

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